Indication & Dosage |
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Oral |
POSTMENOPAUSAL OSTEOPOROSIS |
Adult:
2 g daily. |
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Administration |
Should be taken on an empty stomach (i.e. At least one hour before food or four hours after food). (Take on an empty stomach between meals, preferably at bedtime at least 2 hr after food, milk, milk products or Ca supplements. Mix only w/ plain water & drink immediately.) |
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Precautions |
Not recommended for use in patients with CrCl <30 ml/min. Patients at increased risk of venous thromboembolism. |
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Adverse Drug Reactions |
Nausea and diarrhoea. Headache, loose stools and eczema. Transient reversible increases in creatine kinase activity. |
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Interactions |
Food, milk and derivative products, and medicinal products containing calcium may reduce the bioavailability of strontium ranelate. May reduce the absorption of oral tetracycline and quinolone antibiotics. |
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